Dimethyl Isosorbide

Dimethyl Isosorbide is a non-ionic solvent that is highly miscible with most surfactants, co-solvents, colorants, and peptides. DMI is soluble in many ingredients including water, cottonseed oil, isopropanol, isopropyl myristate, propylene glycol, polysorbate 20, and polysorbate 80; It is insoluble in hydrogenated castor oil, lanolin, mineral oils or silicone oil. It is FDA approved up to 15% in topical over-the-counter products.

Product Details

Formula:

C8H14O4

CAS Number:

5306-85-4

Also Known As:

DMI; 2,5-dimethylisosorbide; Isosorbide dimethyl ether

Structure:

67_Main_Dimethyl_Isosorbide-removebg-preview.png

applications:

Dimethyl Isosorbide is used in various pharmaceutical applications, mainly creams, lotions, and sprays applied to the skin. It is used to stabilize, solvate, and deliver active ingredients into the skin for significantly better penetration and performance. The most common products include anti-acne, ant-aging, self-tanning, and topical ointments.

Typical Specifications

Data is representative of average lots;
data taken from specific lots may vary.

Appearance

Clear colorless liquid

Boiling Point, °C

234

Density, g/cm3

1.15

Flash Point, °C

118

Melting point, °C

-70

Molecular weight, g/mol

174.19

Odor

Mild odor

Purity, %

≥99

Refractive index, n20/D

1.461

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